The Baruch Blumberg Institute is dedicated to advancing research and knowledge in the field of hepatitis B and liver diseases. The Institute was founded in 2003 and today is a leading center for translational research in hepatitis B, liver cancer and related diseases.

The Blumberg Institute is located within the Pennsylvania Biotechnology Center (PABC), which is a 10-acre, four building, 150,000 square foot biotech incubator facility in Doylestown, Pa.

Position Overview:

We are seeking a highly motivated individual with background in synthetic organic chemistry or medicinal chemistry for a full-time Research Associate position in our medicinal chemistry group in the pursuit of novel small molecules to treat chronic hepatitis B virus infection, hemorrhagic fevers, and breast cancer. The successful candidate must have a B.S., M.S. or Ph.D. in organic chemistry or medicinal chemistry, and prior work experience in multistep organic synthesis will be a plus. Under this position you are expected to develop high level of creativity and productivity with strong synthetic problem-solving skills, good laboratory skills and familiarity with modern synthetic techniques and instrumentation (LC-MS, HPLC, NMR, chromatograph). Due to the multi-disciplinary nature of the work, communication skills are also desired.  The Baruch S. Blumberg Institute, formerly the Institute for Hepatitis and Virus Research, is the world’s leading nonprofit research organization dedicated to hepatitis B and liver cancer and is an equal opportunity employer.

Key Duties and Responsibilities:

• Design and execute multi-step syntheses, optimizing and troubleshooting synthetic methods to provide small molecules for biological testing
• Interpret experimental data, from a variety of analytical techniques, with a high degree of reliability and accuracy
• Exercise good judgement to prioritize work, considering feasibility, priorities and project impact
• Present and share results within the group and project team
• Write manuscripts for publication and present findings at conferences

Key skills

• Familiar with the theoretical and practical aspects of synthetic chemistry (synthesis, purification and analytical characterization)
• Excellent oral, written and interpersonal communication skills
• Effective time management skills
• High levels of safety awareness, personal integrity and ethics

Education and Experience:

B.S., M.S. or PhD in organic chemistry or medicinal chemistry, and prior work experience in multistep organic synthesis will be a plus